Efficient cell delivery mediated by lipid-specific endosomal escape of supercharged branched peptides

Various densely charged polycationic species, whether of biological or synthetic origin, can penetrate human cells, albeit with variable efficiencies. The molecular underpinnings involved in such transport remain unclear. Herein, we assemble one, two, or three copies of the HIV peptide TAT on a synt...

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Veröffentlicht in:Traffic
Hauptverfasser: Brock, Dakota J., Kustigian, Lauren, Jiang, Mengqiu, Graham, Kristin, Wang, Ting-Yi, Erazo-Oliveras, Alfredo, Najjar, Kristina, Zhang, Junjie, Rye, Hays, Pellois, Jean-Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948172/
https://ncbi.nlm.nih.gov/pubmed/29582528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12566
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