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Efficient cell delivery mediated by lipid-specific endosomal escape of supercharged branched peptides

Various densely charged polycationic species, whether of biological or synthetic origin, can penetrate human cells, albeit with variable efficiencies. The molecular underpinnings involved in such transport remain unclear. Herein, we assemble one, two, or three copies of the HIV peptide TAT on a synt...

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Detalhes bibliográficos
Publicado no:Traffic
Main Authors: Brock, Dakota J., Kustigian, Lauren, Jiang, Mengqiu, Graham, Kristin, Wang, Ting-Yi, Erazo-Oliveras, Alfredo, Najjar, Kristina, Zhang, Junjie, Rye, Hays, Pellois, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5948172/
https://ncbi.nlm.nih.gov/pubmed/29582528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12566
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