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Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients

Mutations in KRAS exon 2, BRAF and PIK3CA are commonly present in colorectal cancer (CRC) worldwide, but few data about RAS mutations outside KRAS exon 2 are available for Chinese CRCs. We, therefore, determined the mutation frequencies and prognostic values of KRAS exon 2, 3 and 4, NRAS exon 2 and...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Guo, Fang, Gong, Hai, Zhao, Huanhuan, Chen, Jing, Zhang, Yiming, Zhang, Lihua, Shi, Xin, Zhang, Aifeng, Jin, Hui, Zhang, Jianqiong, He, Youji
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904111/
https://ncbi.nlm.nih.gov/pubmed/29666387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24306-1
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