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Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients

Mutations in KRAS exon 2, BRAF and PIK3CA are commonly present in colorectal cancer (CRC) worldwide, but few data about RAS mutations outside KRAS exon 2 are available for Chinese CRCs. We, therefore, determined the mutation frequencies and prognostic values of KRAS exon 2, 3 and 4, NRAS exon 2 and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guo, Fang, Gong, Hai, Zhao, Huanhuan, Chen, Jing, Zhang, Yiming, Zhang, Lihua, Shi, Xin, Zhang, Aifeng, Jin, Hui, Zhang, Jianqiong, He, Youji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904111/
https://ncbi.nlm.nih.gov/pubmed/29666387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24306-1
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