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Mutation status and prognostic values of KRAS, NRAS, BRAF and PIK3CA in 353 Chinese colorectal cancer patients

Mutations in KRAS exon 2, BRAF and PIK3CA are commonly present in colorectal cancer (CRC) worldwide, but few data about RAS mutations outside KRAS exon 2 are available for Chinese CRCs. We, therefore, determined the mutation frequencies and prognostic values of KRAS exon 2, 3 and 4, NRAS exon 2 and...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Guo, Fang, Gong, Hai, Zhao, Huanhuan, Chen, Jing, Zhang, Yiming, Zhang, Lihua, Shi, Xin, Zhang, Aifeng, Jin, Hui, Zhang, Jianqiong, He, Youji
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5904111/
https://ncbi.nlm.nih.gov/pubmed/29666387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24306-1
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