Mutations of KRAS, NRAS, BRAF, EGFR, and PIK3CA genes in urachal carcinoma: Occurence and prognostic significance

PURPOSE: Targeted therapy represents an attractive alternative for rare tumors such as urachal carcinoma (UrC). The aim of this study was to assess the mutations of the most commonly affected 5 genes in the targetable EGFR-pathway in UrC and comapre their frequencies to those of found in urothelial...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Módos, Orsolya, Reis, Henning, Niedworok, Christian, Rübben, Herbert, Szendröi, Attila, Marcell A., Szász, Tímár, József, Baghy, Kornélia, Kovalszky, Ilona, Golabek, Tomasz, Chlosta, Piotr, Okon, Krzysztof, Peyronnet, Benoit, Mathieu, Romain, Shariat, Shahrokh F., Hollósi, Péter, Nyirády, Péter, Szarvas, Tibor
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper: Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129933/
https://ncbi.nlm.nih.gov/pubmed/27283768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9828
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