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Oxidant Stress and Lipid Peroxidation in Acetaminophen Hepatotoxicity
Acetaminophen (APAP) overdose is the most frequent cause of liver injury and acute liver failure in many western countries. The mechanism of APAP-induced hepatocyte necrosis has been investigated extensively. The formation of a reactive metabolite and its binding to cellular proteins was initially t...
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| Pubblicato in: | React Oxyg Species (Apex) |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5903282/ https://ncbi.nlm.nih.gov/pubmed/29682614 |
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