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Building a Safer and Faster CAR: Seatbelts, Airbags and CRISPR

Therapeutic T cell engineering has recently garnered widespread interest owing to the success of CD19 (Chimeric Antigen Receptor) CAR therapy. CARs are synthetic receptors for antigen that redirect the specificity and reprogram the function of the T cells in which they are genetically introduced. CA...

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Bibliografske podrobnosti
izdano v:Biol Blood Marrow Transplant
Main Authors: Perales, Miguel-Angel, Kebriaei, Partow, Kean, Leslie S., Sadelain, Michel
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901894/
https://ncbi.nlm.nih.gov/pubmed/29032264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2017.10.017
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