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Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium
Goblet cell hyperplasia is a common feature of chronic obstructive pulmonary disease (COPD) airways, but the mechanisms that underlie this epithelial remodelling in COPD are not understood. Based on our previous finding of hypoxia-inducible factor-1α (HIF-1α) nuclear localization in large airways fr...
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| Pubblicato in: | J Pathol |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5901746/ https://ncbi.nlm.nih.gov/pubmed/21557221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2863 |
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