Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease

Secretory immunoglobulin A (SIgA) reaches the airway lumen by local transcytosis across airway epithelial cells or with tracheobronchial submucosal gland secretions. In chronic obstructive pulmonary disease (COPD), deficiency of SIgA on the airway surface has been reported, however, reduction of SIg...

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Bibliografische gegevens
Gepubliceerd in:Virchows Arch
Hoofdauteurs: Du, Rui-Hong, Richmond, Bradley, Blackwell, Timothy S., Cates, Justin M., Massion, Pierre P., Ware, Lorraine B., Lee, Jae Woo, Kononov, Alexey V., Lawson, William E., Polosukhin, Vasiliy V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081073/
https://ncbi.nlm.nih.gov/pubmed/26432569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-015-1854-0
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