Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease

Secretory immunoglobulin A (SIgA) reaches the airway lumen by local transcytosis across airway epithelial cells or with tracheobronchial submucosal gland secretions. In chronic obstructive pulmonary disease (COPD), deficiency of SIgA on the airway surface has been reported, however, reduction of SIg...

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Publicat a:Virchows Arch
Autors principals: Du, Rui-Hong, Richmond, Bradley, Blackwell, Timothy S., Cates, Justin M., Massion, Pierre P., Ware, Lorraine B., Lee, Jae Woo, Kononov, Alexey V., Lawson, William E., Polosukhin, Vasiliy V.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081073/
https://ncbi.nlm.nih.gov/pubmed/26432569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-015-1854-0
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