Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD

Although activation of adaptive immunity is a common pathological feature of chronic obstructive pulmonary disease (COPD), particularly during later stages of the disease, the underlying mechanisms are poorly understood. In small airways of COPD patients, we found that localized disruption of the se...

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Bibliografiset tiedot
Julkaisussa:Mucosal Immunol
Päätekijät: Richmond, Bradley W., Mansouri, Samira, Serezani, Ana, Novitskiy, Sergey, Blackburn, Jessica B., Du, Rui-Hong, Fuseini, Hubaida, Gutor, Sergey, Han, Wei, Schaff, Jacob, Vasiukov, Georgii, Xin, Matthew K., Newcomb, Dawn C., Jin, Lei, Blackwell, Timothy S., Polosukhin, Vasiliy V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group US 2020
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946625/
https://ncbi.nlm.nih.gov/pubmed/32968197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-020-00344-9
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