Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD

Although activation of adaptive immunity is a common pathological feature of chronic obstructive pulmonary disease (COPD), particularly during later stages of the disease, the underlying mechanisms are poorly understood. In small airways of COPD patients, we found that localized disruption of the se...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Richmond, Bradley W., Mansouri, Samira, Serezani, Ana, Novitskiy, Sergey, Blackburn, Jessica B., Du, Rui-Hong, Fuseini, Hubaida, Gutor, Sergey, Han, Wei, Schaff, Jacob, Vasiukov, Georgii, Xin, Matthew K., Newcomb, Dawn C., Jin, Lei, Blackwell, Timothy S., Polosukhin, Vasiliy V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946625/
https://ncbi.nlm.nih.gov/pubmed/32968197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-020-00344-9
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