Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD

Although activation of adaptive immunity is a common pathological feature of chronic obstructive pulmonary disease (COPD), particularly during later stages of the disease, the underlying mechanisms are poorly understood. In small airways of COPD patients, we found that localized disruption of the se...

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Foilsithe in:Mucosal Immunol
Main Authors: Richmond, Bradley W., Mansouri, Samira, Serezani, Ana, Novitskiy, Sergey, Blackburn, Jessica B., Du, Rui-Hong, Fuseini, Hubaida, Gutor, Sergey, Han, Wei, Schaff, Jacob, Vasiukov, Georgii, Xin, Matthew K., Newcomb, Dawn C., Jin, Lei, Blackwell, Timothy S., Polosukhin, Vasiliy V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group US 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946625/
https://ncbi.nlm.nih.gov/pubmed/32968197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-020-00344-9
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