Monocyte-derived dendritic cells link localized secretory IgA deficiency to adaptive immune activation in COPD

Although activation of adaptive immunity is a common pathological feature of chronic obstructive pulmonary disease (COPD), particularly during later stages of the disease, the underlying mechanisms are poorly understood. In small airways of COPD patients, we found that localized disruption of the se...

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Pubblicato in:Mucosal Immunol
Autori principali: Richmond, Bradley W., Mansouri, Samira, Serezani, Ana, Novitskiy, Sergey, Blackburn, Jessica B., Du, Rui-Hong, Fuseini, Hubaida, Gutor, Sergey, Han, Wei, Schaff, Jacob, Vasiukov, Georgii, Xin, Matthew K., Newcomb, Dawn C., Jin, Lei, Blackwell, Timothy S., Polosukhin, Vasiliy V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group US 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946625/
https://ncbi.nlm.nih.gov/pubmed/32968197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-020-00344-9
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