Gas6/MerTK signaling is negatively regulated by NF-κB and supports lung carcinogenesis

Growth arrest-specific 6 (Gas6) has been implicated in carcinogenesis through activation of its receptors, particularly MerTK. To investigate whether Gas6 plays a role in resistance to NF-κB inhibitors, which have not proven to be effective agents for lung cancer therapy, we studied lung cancer mode...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Novitskiy, Sergey V., Zaynagetdinov, Rinat, Vasiukov, Georgii, Gutor, Sergey, Han, Wei, Serezani, Ana, Matafonov, Anton, Gleaves, Linda A., Sherrill, Taylor P., Polosukhin, Vasiliy V., Blackwell, Timothy S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2019
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925028/
https://ncbi.nlm.nih.gov/pubmed/31903163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27345
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