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Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium

Goblet cell hyperplasia is a common feature of chronic obstructive pulmonary disease (COPD) airways, but the mechanisms that underlie this epithelial remodelling in COPD are not understood. Based on our previous finding of hypoxia-inducible factor-1α (HIF-1α) nuclear localization in large airways fr...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Polosukhin, Vasiliy V, Cates, Justin M, Lawson, William E, Milstone, Aaron P, Matafonov, Anton G, Massion, Pierre P, Lee, Jae Woo, Randell, Scott H, Blackwell, Timothy S
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901746/
https://ncbi.nlm.nih.gov/pubmed/21557221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2863
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