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NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection
Pneumococcal infections are the eigth leading cause of death in the United States, and it is estimated that older patients (≥65 yr of age) account for the most serious cases. The goal of our current study is to understand the impact of biological aging on innate immune responses to Streptococcus pne...
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| 發表在: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5900358/ https://ncbi.nlm.nih.gov/pubmed/29097427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00393.2017 |
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