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Decreased NLRP3 Inflammasome Expression in Aged Lung may contribute to Increased Susceptibility to Secondary Streptococcus pneumoniae Infection

Post-viral pneumococcal pneumonia is a leading morbidity and mortality in older patients (≥ 65 years of age). The goal of our current study is to understand the impact of chronological aging on innate immune responses to a secondary, post viral infection with Streptococcus pneumoniae, a causative ag...

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Bibliographic Details
Published in:Exp Gerontol
Main Authors: Cho, Soo Jung, Plataki, Maria, Mitzel, Dana, Lowry, Gena, Rooney, Kristen, Stout-Delgado, Heather
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869149/
https://ncbi.nlm.nih.gov/pubmed/29203400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2017.11.010
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