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NLRP3 inflammasome activation in aged macrophages is diminished during Streptococcus pneumoniae infection

Pneumococcal infections are the eigth leading cause of death in the United States, and it is estimated that older patients (≥65 yr of age) account for the most serious cases. The goal of our current study is to understand the impact of biological aging on innate immune responses to Streptococcus pne...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Lung Cell Mol Physiol
Huvudupphovsmän: Cho, Soo Jung, Rooney, Kristen, Choi, Augustine M. K., Stout-Delgado, Heather W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900358/
https://ncbi.nlm.nih.gov/pubmed/29097427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00393.2017
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