Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with NLRP3 Inflammasome Activation

Aging has been implicated in the development of pulmonary fibrosis, which has seen a sharp increase in incidence in those older than 50 years. Recent studies demonstrate a role for the nucleotide-binding domain and leucine rich repeat containing family, pyrin domain containing 3 (NLRP3) inflammasome...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Stout-Delgado, Heather W., Cho, Soo Jung, Chu, Sarah G., Mitzel, Dana N., Villalba, Julian, El-Chemaly, Souheil, Ryter, Stefan W., Choi, Augustine M. K., Rosas, Ivan O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979364/
https://ncbi.nlm.nih.gov/pubmed/26933834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0222OC
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