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DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) has been linked to chronic lung inflammation. Drosha ribonuclease III (DROSHA), a class 2 ribonuclease III enzyme, plays a key role in microRNA (miRNA) biogenesis. However, the mechanisms by which DROSHA affects the lung inflammation during idiopathic pulmonary fi...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Cho, Soo Jung, Hong, Kyoung Sook, Jeong, Ji Hun, Lee, Mihye, Choi, Augustine M. K., Stout-Delgado, Heather W., Moon, Jong-Seok
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721825/
https://ncbi.nlm.nih.gov/pubmed/31434287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080938
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