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GLUT1-dependent glycolysis regulates exacerbation of fibrosis via AIM2 inflammasome activation
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a rapidly progressive, fatal lung disease that affects older adults. One of the detrimental natural histories of IPF is acute exacerbation of IPF (AE-IPF), of which bacterial infection is reported to play an important role. However, the mechanism by...
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| Published in: | Thorax |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BMJ Publishing Group
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7063401/ https://ncbi.nlm.nih.gov/pubmed/31822523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2019-213571 |
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