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mTORC1 induced HK1-dependent glycolysis regulates NLRP3 inflammasome activation
The mammalian target of rapamycin complex 1 (mTORC1) regulates activation of immune cells and cellular energy metabolism. While glycolysis has been linked to immune functions, the mechanisms by which glycolysis regulates NLRP3 inflammasome activation remain unclear. Here, we demonstrate that mTORC1-...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858438/ https://ncbi.nlm.nih.gov/pubmed/26119735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.05.046 |
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