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UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis
Cellular lipid metabolism has been linked to immune responses; however, the precise mechanisms by which de novo fatty acid synthesis can regulate inflammatory responses remain unclear. The NLRP3 inflammasome serves as a platform for caspase-1–dependent maturation and secretion of proinflammatory cyt...
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| Izdano u: | J Clin Invest |
|---|---|
| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319445/ https://ncbi.nlm.nih.gov/pubmed/25574840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78253 |
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