UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

Cellular lipid metabolism has been linked to immune responses; however, the precise mechanisms by which de novo fatty acid synthesis can regulate inflammatory responses remain unclear. The NLRP3 inflammasome serves as a platform for caspase-1–dependent maturation and secretion of proinflammatory cyt...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Moon, Jong-Seok, Lee, Seonmin, Park, Mi-Ae, Siempos, Ilias I., Haslip, Maria, Lee, Patty J., Yun, Mijin, Kim, Chun K., Howrylak, Judie, Ryter, Stefan W., Nakahira, Kiichi, Choi, Augustine M.K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319445/
https://ncbi.nlm.nih.gov/pubmed/25574840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78253
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados