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Dampening insulin signaling by an NLRP3 ‘meta-flammasome’
The inflammasome has been linked to metabolic disorders such as obesity and type 2 diabetes. Data now suggest that the crosstalk between the inflammasome and autophagy critically mediates cytoplasmic receptor NLRP3–dependent activation of the inflammasome by the saturated fatty acids contained in a...
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| Udgivet i: | Nat Immunol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6240333/ https://ncbi.nlm.nih.gov/pubmed/21502990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2028 |
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