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NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages
Metabolic regulation has been implicated in the pathogenesis of inflammatory diseases. NADPH oxidase 4 (NOX4), a source of cellular superoxide anion, has multiple biological functions that may be of importance in inflammation, and in the pathogenesis of human metabolic diseases, including diabetes....
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| Publicado en: | Nat Med |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5204248/ https://ncbi.nlm.nih.gov/pubmed/27455510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4153 |
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