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Age Enhanced ER Stress Contributes to Increased Atg9A Inhibition of STING Mediated IFNβ Production during Streptococcus Pneumoniae Infection
Pneumococcal infections remain a leading cause of death in persons ≥ 65 years of age. Recent reports have illustrated detrimental changes in the ER stress response or unfolded protein response (UPR) in aging and age-related diseases; however the relationship between aging, the UPR, and innate immune...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007355/ https://ncbi.nlm.nih.gov/pubmed/24670807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303090 |
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