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Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling
The ability of G protein-coupled receptors (GPCRs) to initiate complex cascades of cellular signaling is governed by the sequential coupling of three main transducer proteins, G protein, GPCR kinase (GRK), and β-arrestin. Mounting evidence indicates these transducers all have distinct conformational...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899476/ https://ncbi.nlm.nih.gov/pubmed/29581292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722336115 |
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