Discovery Of Methylated Circulating DNA Biomarkers For Comprehensive Non-Invasive Monitoring Of Treatment Response In Metastatic Colorectal Cancer

OBJECTIVE: The evaluation of mutations in cell free circulating DNA (cfDNA) has recently been used for tracking disease relapse in colorectal cancer (CRC). This approach requires personalized assay design due to the lack of universally mutated genes. In contrast, early methylation alterations are re...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Barault, Ludovic, Amatu, Alessio, Siravegna, Giulia, Ponzetti, Agostino, Moran, Sebastian, Cassingena, Andrea, Mussolin, Benedetta, Falcomatà, Chiara, Binder, Alexandra, Cristiano, Carmen, Oddo, Daniele, Cancelliere, Carlotta, Bustreo, Sara, Bencardino, Katia, Maden, Sean, Vanzati, Alice, Zavattari, Patrizia, Truini, Mauro, Grady, William M., Racca, Patrizia, Michels, Karin B., Siena, Salvatore, Esteller, Manel, Bardelli, Alberto, Sartore-Bianchi, Andrea, Di Nicolantonio, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897187/
https://ncbi.nlm.nih.gov/pubmed/28982739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313372
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