Nalaganje...
MCM2–7-dependent cohesin loading during S phase promotes sister-chromatid cohesion
DNA replication transforms cohesin rings dynamically associated with chromatin into the cohesive form to establish sister-chromatid cohesion. Here, we show that, in human cells, cohesin loading onto chromosomes during early S phase requires the replicative helicase MCM2–7 and the kinase DDK. Cohesin...
Shranjeno v:
| izdano v: | eLife |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
eLife Sciences Publications, Ltd
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5897099/ https://ncbi.nlm.nih.gov/pubmed/29611806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33920 |
| Oznake: |
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