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Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima
Most transcription factors (TFs) can bind to a population of sequences closely related to a single optimal site. However, some TFs can bind to two distinct sequences that represent two local optima in the Gibbs free energy of binding (ΔG). To determine the molecular mechanism behind this effect, we...
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| Опубликовано в: : | eLife |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications, Ltd
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5896879/ https://ncbi.nlm.nih.gov/pubmed/29638214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32963 |
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