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Preparation and in vitro/in vivo evaluation of PLGA microspheres containing norquetiapine for long-acting injection
BACKGROUND: Norquetiapine (N-desalkyl quetiapine, NQ) is an active metabolite of quetiapine with stable pharmacokinetic and pharmacological properties. However, its short half-life is a drawback for clinical applications, and long-acting formulations are required. PURPOSE: The objectives of this stu...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5896679/ https://ncbi.nlm.nih.gov/pubmed/29670329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S151437 |
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