Preparation and in vivo/in vitro characterization of Ticagrelor PLGA sustained-release microspheres for injection

The objective of this paper was to develop a PLGA carrier Ticagrelor sustained-release microspheres preparation, which was expected to continue to release Ticagrelor for 14 days with a high encapsulation rate. Ticagrelor microspheres were prepared successfully with average diameter of 7.31 µm, drug...

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Bibliografiske detaljer
Main Authors: Linkun Hao, Yunying Jiang, Ru Zhang, Ningning Zhang, Yang Yang, Ying Gao, Yimin Song
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2021-01-01
Serier:Designed Monomers and Polymers
Fag:
ticagrelor
plga
sustained-release
microspheres
stability
in vivo and in vitro correlation
injection
Online adgang:http://dx.doi.org/10.1080/15685551.2021.1984008
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