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In Vitro and In Vivo Evaluations of PLGA Microspheres Containing Nalmefene

Poor patient compliance, untoward reactions and unstable blood drug levels after the bolus administration are impeding the pharmacotherapy for insobriety. A long-acting preparation may address these limitations. The aim of this paper was to further investigate the in vitro characteristics and in viv...

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Pubblicato in:PLoS One
Autori principali: Xie, Xiangyang, Lin, Wen, Xing, Chuanfeng, Yang, Yanfang, Chi, Qiang, Zhang, Hui, Li, Ying, Li, Zhiping, Yang, Yang, Yang, Zhenbo, Li, Mingyuang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418713/
https://ncbi.nlm.nih.gov/pubmed/25938514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125953
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