Biocompatible PLGA-Mesoporous Silicon Microspheres for the Controlled Release of BMP-2 for Bone Augmentation

Bone morphogenetic protein-2 (BMP-2) has been demonstrated to be one of the most vital osteogenic factors for bone augmentation. However, its uncontrolled administration has been associated with catastrophic side effects, which compromised its clinical use. To overcome these limitations, we aimed at...

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Detalhes bibliográficos
Main Authors: Silvia Minardi, Joseph S. Fernandez-Moure, Dongmei Fan, Matthew B. Murphy, Iman K. Yazdi, Xuewu Liu, Bradley K. Weiner, Ennio Tasciotti
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-02-01
Colecção:Pharmaceutics
Assuntos:
bmp-2
silicon
microsphere
plga
bone regeneration
controlled release
Acesso em linha:https://www.mdpi.com/1999-4923/12/2/118
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