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Minimizing acylation of peptides in PLGA microspheres
The main objective of this study was to characterize and find mechanisms to prevent acylation of therapeutic peptides encapsulated in glucose-star poly(D,L-lactic-co-glycolic acid) (PLGA) microspheres. The effect of addition of divalent cation salts CaCl(2), MnCl(2) as well as carboxymethyl chitosan...
में बचाया:
| में प्रकाशित: | J Control Release |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4261194/ https://ncbi.nlm.nih.gov/pubmed/22546683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.04.022 |
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