ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response

Tumor stroma has an active role in the initiation, growth, and propagation of many tumor types by secreting growth factors and modulating redox status of the microenvironment. Although PPARβ/δ in fibroblasts was shown to modulate oxidative stress in the wound microenvironment, there has been no evid...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncogene
Auteurs principaux: Tan, Eddie Han Pin, Sng, Ming Keat, How, Ivan Shun Bo, Chan, Jeremy Soon Kiat, Chen, Jiapeng, Tan, Chek Kun, Wahli, Walter, Tan, Nguan Soon
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Brief Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895604/
https://ncbi.nlm.nih.gov/pubmed/29367760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0109-8
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