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The Potential of the FSP1cre-Pparb/d(−/−) Mouse Model for Studying Juvenile NAFLD

Non-alcoholic fatty liver disease (NAFLD) can progress from steatosis to non-alcoholic steatohepatitis (NASH) characterized by liver inflammation, possibly leading to cirrhosis and hepatocellular carcinoma (HCC). Mice with impaired macrophage activation, when fed a high-fat diet, develop severe NASH...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Chen, Jiapeng, Zhuang, Yan, Sng, Ming Keat, Tan, Nguan Soon, Wahli, Walter
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830345/
https://ncbi.nlm.nih.gov/pubmed/31618976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20205115
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