Conditional knockout of N-WASP in mouse fibroblast caused keratinocyte hyper proliferation and enhanced wound closure

Neural-Wiskott Aldrich Syndrome Protein (N-WASP) is expressed ubiquitously, regulates actin polymerization and is essential during mouse development. We have previously shown that N-WASP is critical for cell-ECM adhesion in fibroblasts. To characterize the role of N-WASP in fibroblast for skin devel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jain, Neeraj, Kalailingam, Pazhanichamy, Tan, Kai Wei, Tan, Hui Bing, Sng, Ming Keat, Chan, Jeremy Soon Kiat, Tan, Nguan Soon, Thanabalu, Thirumaran
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133560/
https://ncbi.nlm.nih.gov/pubmed/27909303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38109
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