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ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response
Tumor stroma has an active role in the initiation, growth, and propagation of many tumor types by secreting growth factors and modulating redox status of the microenvironment. Although PPARβ/δ in fibroblasts was shown to modulate oxidative stress in the wound microenvironment, there has been no evid...
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| Udgivet i: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5895604/ https://ncbi.nlm.nih.gov/pubmed/29367760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0109-8 |
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