Regulation of epithelial–mesenchymal IL-1 signaling by PPARβ/δ is essential for skin homeostasis and wound healing

Skin morphogenesis, maintenance, and healing after wounding require complex epithelial–mesenchymal interactions. In this study, we show that for skin homeostasis, interleukin-1 (IL-1) produced by keratinocytes activates peroxisome proliferator–activated receptor β/δ (PPARβ/δ) expression in underlyin...

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Detalhes bibliográficos
Main Authors: Chong, Han Chung, Tan, Ming Jie, Philippe, Virginie, Tan, Siew Hwey, Tan, Chek Kun, Ku, Chee Wai, Goh, Yan Yih, Wahli, Walter, Michalik, Liliane, Tan, Nguan Soon
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699156/
https://ncbi.nlm.nih.gov/pubmed/19307598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200809028
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