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ROS release by PPARβ/δ-null fibroblasts reduces tumor load through epithelial antioxidant response

Tumor stroma has an active role in the initiation, growth, and propagation of many tumor types by secreting growth factors and modulating redox status of the microenvironment. Although PPARβ/δ in fibroblasts was shown to modulate oxidative stress in the wound microenvironment, there has been no evid...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Tan, Eddie Han Pin, Sng, Ming Keat, How, Ivan Shun Bo, Chan, Jeremy Soon Kiat, Chen, Jiapeng, Tan, Chek Kun, Wahli, Walter, Tan, Nguan Soon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895604/
https://ncbi.nlm.nih.gov/pubmed/29367760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-017-0109-8
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