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Motor neuron degeneration correlates with respiratory dysfunction in SCA1

Spinocerebellar ataxia type 1 (SCA1) is characterized by adult-onset cerebellar degeneration with attendant loss of motor coordination. Bulbar function is eventually impaired and patients typically die from an inability to clear the airway. We investigated whether motor neuron degeneration is at the...

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Detaylı Bibliyografya
Yayımlandı:Dis Model Mech
Asıl Yazarlar: Orengo, James P., van der Heijden, Meike E., Hao, Shuang, Tang, Jianrong, Orr, Harry T., Zoghbi, Huda Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894948/
https://ncbi.nlm.nih.gov/pubmed/29419414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.032623
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