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Loss of Atoh1 from neurons regulating hypoxic and hypercapnic chemoresponses causes neonatal respiratory failure in mice

Atoh1-null mice die at birth from respiratory failure, but the precise cause has remained elusive. Loss of Atoh1 from various components of the respiratory circuitry (e.g. the retrotrapezoid nucleus (RTN)) has so far produced at most 50% neonatal lethality. To identify other Atoh1-lineage neurons th...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: van der Heijden, Meike E, Zoghbi, Huda Y
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067883/
https://ncbi.nlm.nih.gov/pubmed/29972353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38455
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