Comprehensive single cell transcriptional profiling of a multicellular organism

To resolve cellular heterogeneity, we developed a combinatorial indexing strategy to profile the transcriptomes of single cells or nuclei (sci-RNA-seq: Single cell Combinatorial Indexing RNA sequencing). We applied sci-RNA-seq to profile nearly 50,000 cells from the nematode Caenorhabditis elegans a...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Science
Päätekijät: Cao, Junyue, Packer, Jonathan S., Ramani, Vijay, Cusanovich, Darren A., Huynh, Chau, Daza, Riza, Qiu, Xiaojie, Lee, Choli, Furlan, Scott N., Steemers, Frank J., Adey, Andrew, Waterston, Robert H., Trapnell, Cole, Shendure, Jay
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894354/
https://ncbi.nlm.nih.gov/pubmed/28818938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aam8940
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