The crystal structure of the drug target Mycobacterium tuberculosis methionyl-tRNA synthetase in complex with a catalytic intermediate

Mycobacterium tuberculosis is a pathogenic bacterial infectious agent that is responsible for approximately 1.5 million human deaths annually. Current treatment requires the long-term administration of multiple medicines with substantial side effects. Lack of compliance, together with other factors,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Acta Crystallogr F Struct Biol Commun
Main Authors: Barros-Álvarez, Ximena, Turley, Stewart, Ranade, Ranae M., Gillespie, J. Robert, Duster, Nicole A., Verlinde, Christophe L. M. J., Fan, Erkang, Buckner, Frederick S., Hol, Wim G. J.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2018
Teme:
Research Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893993/
https://ncbi.nlm.nih.gov/pubmed/29633973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18003151
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