The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile

Inflammatory bowel disease (IBD) is a chronic condition driven by loss of homeostasis between the mucosal immune system, the commensal gut microbiota, and the intestinal epithelium. Our goal is to understand how these components of the intestinal ecosystem cooperate to control homeostasis. By combin...

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Udgivet i:PLoS Biol
Main Authors: Lyons, Jesse, Ghazi, Phaedra C., Starchenko, Alina, Tovaglieri, Alessio, Baldwin, Katherine R., Poulin, Emily J., Gierut, Jessica J., Genetti, Casie, Yajnik, Vijay, Breault, David T., Lauffenburger, Douglas A., Haigis, Kevin M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892915/
https://ncbi.nlm.nih.gov/pubmed/29596476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2002417
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