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Identification of high affinity HER2 binding antibodies using CHO Fab surface display
Discovery of monoclonal antibodies is most commonly performed using phage or yeast display but mammalian cells are used for production because of the complex antibody structure, including the multiple disulfide bonds and glycosylation, required for function. As this transition between host organisms...
Guardat en:
| Publicat a: | Protein Eng Des Sel |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5892863/ https://ncbi.nlm.nih.gov/pubmed/29566240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzy004 |
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