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Identification of high affinity HER2 binding antibodies using CHO Fab surface display
Discovery of monoclonal antibodies is most commonly performed using phage or yeast display but mammalian cells are used for production because of the complex antibody structure, including the multiple disulfide bonds and glycosylation, required for function. As this transition between host organisms...
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| Publicado no: | Protein Eng Des Sel |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5892863/ https://ncbi.nlm.nih.gov/pubmed/29566240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzy004 |
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