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Efficient Recovery of High-Affinity Antibodies from a Single-Chain Fab Yeast Display Library

Yeast display is a powerful technology for the isolation of monoclonal antibodies (mAbs) against a target antigen. Antibody libraries have been displayed on the surface of yeast as both single-chain variable fragment (scFv) and antigen binding fragment (Fab). Here, we combine these two formats to di...

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Détails bibliographiques
Publié dans:J Mol Biol
Auteurs principaux: Walker, Laura M., Bowley, Diana R., Burton, Dennis R.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332843/
https://ncbi.nlm.nih.gov/pubmed/19376130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.019
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