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Fab is the most efficient format to express functional antibodies by yeast surface display

Multiple formats are available for engineering of monoclonal antibodies (mAbs) by yeast surface display, but they do not all lead to efficient expression of functional molecules. We therefore expressed four anti-tumor necrosis factor and two anti-IpaD mAbs as single-chain variable fragment (scFv), a...

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Bibliografske podrobnosti
izdano v:MAbs
Main Authors: Sivelle, Coline, Sierocki, Raphaël, Ferreira-Pinto, Kelly, Simon, Stéphanie, Maillere, Bernard, Nozach, Hervé
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6150635/
https://ncbi.nlm.nih.gov/pubmed/29708852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1468952
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