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SIRT2 deacetylase represses NFAT transcription factor to maintain cardiac homeostasis
Heart failure is an aging-associated disease that is the leading cause of death worldwide. Sirtuin family members have been largely studied in the context of aging and aging-associated diseases. Sirtuin 2 (SIRT2) is a cytoplasmic protein in the family of sirtuins that are NAD(+)-dependent class III...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5892579/ https://ncbi.nlm.nih.gov/pubmed/29440391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000915 |
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