SIRT2 deacetylase represses NFAT transcription factor to maintain cardiac homeostasis

Heart failure is an aging-associated disease that is the leading cause of death worldwide. Sirtuin family members have been largely studied in the context of aging and aging-associated diseases. Sirtuin 2 (SIRT2) is a cytoplasmic protein in the family of sirtuins that are NAD(+)-dependent class III...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sarikhani, Mohsen, Maity, Sangeeta, Mishra, Sneha, Jain, Aditi, Tamta, Ankit K., Ravi, Venkatraman, Kondapalli, Mrudula S., Desingu, Perumal A., Khan, Danish, Kumar, Shweta, Rao, Swathi, Inbaraj, Meena, Pandit, Anwit S., Sundaresan, Nagalingam Ravi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892579/
https://ncbi.nlm.nih.gov/pubmed/29440391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000915
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